Validation of GEANT4 for Accurate Modeling of $^{111}$In SPECT Acquisition

نویسندگان

  • Bernd Schweizer
  • Andreas Goedicke
چکیده

Quantitative SPECT imaging of In is of growing importance in nuclear medicine applications like patient-specific radionuclide dosimetry. In this study, the quality of a Monte-Carlo based model of the imaging chain from nuclear decay to detection in a gamma camera is investigated. Important characteristics like the camera point spread function (PSF), the phantom attenuation and scatter effects are compared between simulation and experiment. The model shows a good agreement to the actual measurements and allows for further use in the development of quantitative SPECT reconstruction which will be mandatory for future oncology.

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تاریخ انتشار 2010